Initiate the RegulatoryNetwork object.

initiate_grn(object, ...)

# S3 method for Seurat
initiate_grn(
  object,
  regions = NULL,
  peak_assay = "peaks",
  rna_assay = "RNA",
  exclude_exons = TRUE
)

Arguments

regions

Candidate regions to consider for binding site inference. If NULL, all peaks regions are considered.

peak_assay

A character vector indicating the name of the chromatin accessibility assay in the Seurat object.

rna_assay

A character vector indicating the name of the gene expression assay in the Seurat object.

exclude_exons

Logical. Whether to consider exons for binding site inference.

Value

A SeuratPlus object containing a RegulatoryNetwork object.