Main workflowFunctions executing the main Pando workflow |
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Initiate the |
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Scan for motifs in candidate regions. |
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Infer a Gene Regulatory Network with |
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Find TF modules in regulatory network |
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VisualizationFunctions to visualize the GRN |
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Compute network graph embedding using UMAP. |
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Get sub-network centered around one TF. |
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Compute UMAP embedding |
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Plot goodness-of-fit metrics. |
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Plot module metrics number of genes, number of peaks and number of TFs per gene. |
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Plot network graph. |
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Plot sub-network centered around one TF. |
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Object interactionFunctions to interact with Seurat and Network objects |
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Get network data |
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Get network |
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The Modules class |
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Get network features |
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Get network parameters |
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Get TF modules |
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Get network parameters |
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Get network regions |
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Get network TFs |
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Get GRN inference parameters |
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Get fitted coefficients |
Get goodness-of-fit info |
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Print RegulatoryNetwork objects |
The Regions class |
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The RegularotyNetwork class |
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The SeuratPlus class |
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Get summary of seurat assay |
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Model fittingFunctions to fit models |
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Fit a bagging ridge regression model as implemented in scikit-learn (python) |
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Fit a bayesian ridge regression model as implemented in scikit-learn (python) |
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Fit a Bayesian regression model with brms and Stan |
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Cross-validation for regularized generalized linear models |
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Fit generalized linear model |
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Fit regularized generalized linear model |
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Fit models for gene expression |
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Fit (regularized) generalized linear model |
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Fit a gradient boosting regression model with XGBoost |
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UtilitiesUtility functions |
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Aggregate matrix over groups |
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Aggregate Seurat assay over groups |
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Apply function over a List or Vector (in parallel) |
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Safe correlation function which returns a sparse matrix without missing values |
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Find peaks or regions near gene body or TSS |